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EPSRC Centre for Doctoral Training in Fluid Dynamics

Computational and experimental evaluation of a novel assistive cardio-vascular device

Lead Academic Supervisor

Ali Alazmani (School of Mechanical Engineering) and Zinedine Khatir (School of Mechanical Engineering)

Lead Industrial Supervisor

Osama Jaber (Leeds General Infirmary)

Co-Supervisor(s)

Peter Culmer (School of Mechanical Engineering) and Daniel Lesnic (School of Mathematics)

Theme(s)

Bio-Engineering/Medical Fluid Flows

Summary

This project aims to investigate the effectiveness of a novel flow control device to treat single ventricle heart defects, using Computational Fluid Dynamics (CFD) simulations combined with fluid flow-enabled robotics. In particular, we explore how soft flexible non-blood-contacting Fontan (i.e. deformable tube to by-pass the non-functional ventricle and establish a direct connection between the systemic venous and pulmonary arterial circulations) affects the different fluid dynamics and univentricular circulation in such peculiar fluid flow geometries.

 
 

 

 

 

 


Illustration: Geometry and flow circulation

Together with CFD, we will use robotics-enabled experimentation together with geometric MRI data  to develop the computational flow models and an active cardio-vascular system in this project. This study is expected to make a fundamentally important contribution to the science of implantable systems and may have a medically significant impact on the design of new cavopulmonary assistance technologies.